发明名称 |
GLUCAN GELS |
摘要 |
The present invention relates to a glucan having a weight average molar mass of 15,000 to 50,000 g/mol on a single chain basis and a weight average molar mass in aqueous solution on an aggregate basis of 4 to 20×105 g/mol and existing in gel form in aqueous solution at a concentration ≧1% at 25° C. and neutral pH and having a melting temperature (gel to sol) of 35 to 60° C. when the glucan is dissolved in water at a concentration of 2%, methods for the production thereof, medical uses thereof, physical supports having the glucan applied thereto or impregnated thereon and in vitro methods of proliferation of skin cells which comprise contacting a population of skin cells with the glucan. |
申请公布号 |
US2016256385(A1) |
申请公布日期 |
2016.09.08 |
申请号 |
US201615066748 |
申请日期 |
2016.03.10 |
申请人 |
BIOTEC PHARMACON ASA |
发明人 |
Engstad Rolf;Solem Stein-Tore;Ramsøy Dag-Eirik |
分类号 |
A61K9/06;A61K9/00;A61L26/00;A61K31/716;A61L15/00 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
1. A method of assisting wound or ulcer healing or treating oral mucositis or cancer in a subject in need thereof which comprises administering to said subject a gel glucan product comprising a soluble yeast glucan in aqueous solution at a concentration of 1 to 6%, the glucan having a weight average molar mass of 15,000 to 50,000 g/mol on a single chain basis and a weight average molar mass in aqueous solution on an aggregate basis of 4 to 20×105 g/mol, the gel glucan product having a gel to sol melting temperature of 35 to 60° C. |
地址 |
Tromso NO |