SHON AS A PROGNOSTIC BIOMARKER FOR CANCER AND AS A PREDICTOR OF RESPONSE TO ENDOCRINE THERAPY
摘要
An estrogen-regulated gene sequence SHON has been characterised, and found to be a novel oncogene in mammary carcinoma and significantly associated with estrogen and progesterone receptor expression in breast cancer. The present invention encompasses methods for predicting the responsiveness to endocrine therapy for breast cancer and providing a prognosis for disease-free and/or distant metastasis-free survival of a cancer patient.
申请公布号
EP2932272(A4)
申请公布日期
2016.09.14
申请号
EP20130846652
申请日期
2013.10.17
申请人
MA, RUNLIN Z;LIU, DONG-XU
发明人
LIU, DONG-XU;ABDEL-FATAH, TAREK MOHAMED AHMED;PERRY, JOHANNA KATE;LU, JUN;HUANG, BAIQU;CHAN, STEPHEN YAN TAT;GREEN, ANDREW RUSSELL;ELLIS,IAN OGILVIE