| 摘要 |
A medicine for preventing and/or treating diseases caused by the activation of caspase-1, for example, chronic inflammations or autoinflammatory diseases, said medicine comprising as an active ingredient a compound represented by formula (I) or (II) [wherein: either R1 or R2 represents a hydroxy group and the other represents a hydrogen atom or a fluorine atom; either R11 or R12 represents a hydroxy group and the other represents a hydrogen atom or a fluorine atom; R3, R4 and R13 represent a hydrogen atom or a fluorine atom; ---- represents a single or double bond; R5, R6, R15 and R16 represent a hydrogen atom, an alkyl group or a fluorine atom; R7 and R17 represent -CH2-OR8, -CH2-OR18, etc.; and R8 and R18 represent a hydrogen atom, etc. or bind respectively to R6 and R16 to form a single bond]. |
