Colloids with valence: fabrication, functionalization and directional bonding

摘要

A method for creating the colloidal analogs of atoms with valence: colloidal particles with chemically distinct surface patches that imitate hybridized atomic orbitals, including sp, sp2, sp3, sp3 d, sp3 d2 and sp3 d3. Functionalized with DNA with single-stranded sticky ends, patches on different particles can form highly directional bonds through programmable, specific and reversible DNA hybridization. These features allow the particles to self-assemble into ‘colloidal molecules’ with triangular, tetrahedral and other bonding symmetries, and should also give access to a rich variety of new microstructured colloidal materials.

主权项

1. A method for creating a colloidal particle of manufacture, comprising the steps of,
providing a plurality of functionalized colloidal particles; assembling functionalized colloidal particles from the plurality of colloidal particles, forming a plurality of functionalized patchy particle having at least one patch comprising an exposed surface of a functionalized colloidal particle of the plurality of colloidal particles; mixing the plurality of functionalized patchy particles, wherein the at least one patch enables selective bonding of a first of the plurality of functionalized patchy particles to a second of the plurality of functionalized patchy particles.