发明名称 |
Toxin in type A <i>Clostridium perfringens</i> |
摘要 |
The present disclosure relates to a novel toxin of Type A C. perfringens and immunogenic compositions and vaccines thereof. The present disclosure further relates to methods and uses of treating or preventing enteric disease and assays for diagnosing enteric disease in mammals. |
申请公布号 |
US9493519(B2) |
申请公布日期 |
2016.11.15 |
申请号 |
US201314402956 |
申请日期 |
2013.05.23 |
申请人 |
University of Guelph |
发明人 |
Prescott John;Gohari Iman Mehdizadeh;Parreira Pinto Valeria |
分类号 |
A61K39/08;C07K14/33;G01N33/569;C07K16/12;C12Q1/68;A61K39/00 |
主分类号 |
A61K39/08 |
代理机构 |
Bereskin & Parr LLP |
代理人 |
Bereskin & Parr LLP ;Szweras Melanie |
主权项 |
1. An isolated polypeptide encoded by a nucleic acid molecule comprising the nucleic acid sequence as shown in SEQ ID NO:1 or a variant thereof that encodes a protein having at least 90% identity to the full length protein encoded by SEQ ID NO:1 or comprising the amino acid sequence as shown in SEQ ID NO:2 or a variant thereof having at least 90% sequence identity to the full length protein as shown in SEQ ID NO:2, wherein the polypeptide is toxoided. |
地址 |
Guelph CA |