发明名称 |
Compositions and methods for treating clostridium difficile-associated diseases |
摘要 |
Described herein are isolated polypeptides each containing one or more receptor-binding sites of toxin A (tcdA) of Clostridium difficile (Cd), nucleic acids encoding the polypeptides, and methods of using the polypeptides and nucleic acids. |
申请公布号 |
US9493518(B2) |
申请公布日期 |
2016.11.15 |
申请号 |
US201414209987 |
申请日期 |
2014.03.13 |
申请人 |
National Health Research Institutes |
发明人 |
Chong Pele Choi-Sing;Huang Jui-Hsin;Leng Chih-Hsiang |
分类号 |
A61K39/39;C07K14/33;A61K38/48;C12N9/52;G01N33/569;A61K39/08;A61K39/00 |
主分类号 |
A61K39/39 |
代理机构 |
Cesari and McKenna LLP |
代理人 |
Cesari and McKenna LLP |
主权项 |
1. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2 or 4, and an N-terminal lipidating sequence that includes the amino acid sequence of SEQ ID NO:20. |
地址 |
Zhunan Town TW |