| 摘要 |
The invention provides high molecular weight, crystalline or semi crystal line biodegradable and biocompatible poly(ester urea) (PEU) polymers useful for making vascular stents and hard tissue replacement implants, such as bon e substitutes. The PE polymers are based on .alpha. amino acids and are made by a polycondensation reaction. PE polymer compositions can contain a thera peutic diol incorporated into the polymer backbone that is released from suc h an implant in situ. Bioactive agents, such as analgesics, antibiotics, and the like, can also be covalently attached to certain PEU polymers for relea se into tissue surrounding an implant during biodegradation of the polymer.< /SDOAB>
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