发明名称 Ansamycin formulations and methods of use thereof
摘要 Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 ("Hsp90").
申请公布号 US2008221077(A1) 申请公布日期 2008.09.11
申请号 US20070001239 申请日期 2007.12.11
申请人 AUSTAD BRIAN C;GRENIER LOUIS;HOLSON EDWARD B;LEE JOHN J;PAK ROGER H;PORTER JAMES R;WRIGHT JAMES L 发明人 AUSTAD BRIAN C.;GRENIER LOUIS;HOLSON EDWARD B.;LEE JOHN J.;PAK ROGER H.;PORTER JAMES R.;WRIGHT JAMES L.
分类号 A61K31/397;A61K31/395;A61K31/40;A61P35/00;C07D225/06 主分类号 A61K31/397
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