发明名称 |
PHARMACEUTICAL COMPOSITION |
摘要 |
Disclosed is a pharmaceutical composition comprising a combination of an Hsp90 family protein inhibitor and at least one compound. The Hsp90 family p rotein inhibitor may be a benzoyl compound represented by the formula (I) [w herein n represents an integer of 1 to 5; R1 represents a substituted or uns ubstituted lower alkyl, CONR7R8 (wherein R7 and R8 independently represent a hydrogen atom, a substituted or unsubstituted lower alkyl or the like), or the like; R2 represents a substituted or unsubstituted aryl or the like; R3 and R5 independently represent a hydrogen atom, a substituted or unsubstitut ed lower alkyl or the like; R4 represents a hydrogen atom, a hydroxyl or a h alogen; and R6 represents a hydrogen atom, a halogen, a substituted or unsub stituted lower alkyl or the like], a prodrug thereof, or a pharmacologically acceptable salt of the benzoyl compound or the prodrug. (I)
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申请公布号 |
CA2680161(A1) |
申请公布日期 |
2008.09.12 |
申请号 |
CA20082680161 |
申请日期 |
2008.03.05 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
NAKASHIMA, TAKAYUKI;ISHII, TOSHIHIKO;SOGA, SHIRO;AKINAGA, SHIRO;SHIOTSU, YUKIMASA |
分类号 |
A61K45/06;A61K31/198;A61K31/337;A61K31/5375;A61K31/5377;A61K38/00;A61K39/395;A61P35/00;A61P35/02;A61P43/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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