主权项 |
1. A system for use in delivering spinal cord stimulation for providing cardiac therapy comprising:
stimulation apparatus configured to provide spinal cord stimulation to a patient, wherein the stimulation apparatus comprises a plurality of electrodes located along the patient's spinal cord, wherein each electrode of the plurality of electrodes is locatable at a different location along the patient's spinal cord, wherein each electrode of the plurality of electrodes is configurable in one of an active state and an inactive state and is further configurable in one of a negative polarity and a positive polarity when in the active state; sensing apparatus configured to monitor one or more parameters related to the patient's heart; and a control module coupled to the sensing apparatus and to the stimulation apparatus and configured to:
define a plurality of electrode array configurations using the plurality of electrodes for use in delivery of spinal cord stimulation, wherein each electrode array configuration of the plurality of electrode array configurations is configured differently than the other electrode array configurations of the plurality of electrode array configurations,use each different electrode array configuration separately from the other electrode array configurations to deliver spinal cord stimulation for cardiac therapy,monitor, using the sensing apparatus, one or more physiological parameters related to the patient's heart during the delivery of spinal cord stimulation from each different electrode array configuration of the plurality of electrode array configurations, andanalyze the one or more physiological parameters monitored during the delivery of spinal cord stimulation from each different electrode array configuration to select an effective electrode array configuration of the plurality of electrode array configurations for use in delivering spinal cord stimulation for cardiac therapy, wherein, to analyze the one or more physiological parameters monitored during the delivery of spinal cord stimulation from each different electrode array configuration to select an effective electrode array configuration, the control module is further configured to:analyze heart rate turbulence during the delivery of spinal cord stimulation from each different electrode array configuration,determine the effectiveness of each different electrode array configuration based on a change in heart rate turbulence, andselect an effective electrode array configuration from the plurality of electrode array configurations for use in delivering spinal cord stimulation for cardiac therapy based on at least the analysis of heart rate turbulence monitored for each different electrode array configuration of the plurality of electrode array configurations, wherein, to select an effective electrode array configuration from the plurality of electrode array configurations for use in delivering spinal cord stimulation for cardiac therapy based on at least the analysis of heart rate turbulence monitored for each different electrode array configuration of the plurality of electrode array configurations, the control module is configured to select an effective electrode array configuration of the plurality of electrode array configurations which, when used to deliver spinal cord stimulation, results in a change in heart rate turbulence that correlates to an improvement in functionality of the heart of the patient. |