发明名称 |
Liquid pharmaceutical formulations of palonosetron |
摘要 |
The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments. |
申请公布号 |
US9439854(B2) |
申请公布日期 |
2016.09.13 |
申请号 |
US201514793233 |
申请日期 |
2015.07.07 |
申请人 |
Helsinn Healthcare SA |
发明人 |
Calderari Giorgio;Bonadeo Daniele;Cannella Roberta;Macciocchi Alberto;Miksztal Andrew;Malefyt Thomas;Lee Kathleen M |
分类号 |
A61K31/47;A61K47/26;A61K31/473;A61K9/08;A61K47/18;A61K47/12;A61K47/00;A61K47/02;A61K9/00;B65B7/16;B65B55/02;A61K47/10 |
主分类号 |
A61K31/47 |
代理机构 |
|
代理人 |
Sullivan Clark G. |
主权项 |
1. A formulation for reducing emesis or reducing the likelihood of emesis in a human, the formulation comprising a pharmaceutical single-use, unit-dose, sterile aqueous intravenous solution comprising palonosetron or a pharmaceutically acceptable salt thereof in a concentration of 0.05 mg/mL based on the weight of the palonosetron free base and in a volume of from 1 mL to 5 mL. |
地址 |
Lugano/Pazzallo CH |