发明名称 IMMOBILIZED PLASMINOGENASE COMPOSITION, PREPARATION PROCESS, USE AND DEVICE COMPRISING SUCH A COMPOSITION
摘要 The invention relates to an enzymatic composition comprising: - at least one enzyme, termed plasminogenase, for converting, into plasmin, plasminogen from a blood plasma medium comprising plasminogen; - a solid support that is insoluble in aqueous solution, the solid support having dimensions suitable for being able to be retained on a filter having a cut-off threshold of less than or equal to 0.22 µm; characterized in that said plasminogenase is bound to the solid support and remains bound to this support on contact with a blood plasma medium and in that the composition is in the dry state. The invention also relates to a process for preparing such an enzymatic composition, to the use thereof and to a device (20) for preparing a blood plasma medium ex vivo rich in sterile plasmin and free of enzymatic composition.
申请公布号 WO2016166484(A1) 申请公布日期 2016.10.20
申请号 WO2016FR50869 申请日期 2016.04.14
申请人 ARCADOPHTA 发明人 REBOUL, Gérard
分类号 C12N11/02;A61K35/16;A61K38/48;C12N9/72;C12N11/08 主分类号 C12N11/02
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