摘要 |
The invention relates to an enzymatic composition comprising: - at least one enzyme, termed plasminogenase, for converting, into plasmin, plasminogen from a blood plasma medium comprising plasminogen; - a solid support that is insoluble in aqueous solution, the solid support having dimensions suitable for being able to be retained on a filter having a cut-off threshold of less than or equal to 0.22 µm; characterized in that said plasminogenase is bound to the solid support and remains bound to this support on contact with a blood plasma medium and in that the composition is in the dry state. The invention also relates to a process for preparing such an enzymatic composition, to the use thereof and to a device (20) for preparing a blood plasma medium ex vivo rich in sterile plasmin and free of enzymatic composition. |