Methods for the treatment of pediatric otic disorders

摘要

Disclosed herein are methods for the treatment of pediatric otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

主权项

1. A method of alleviating, abating or ameliorating a pediatric otic disease or condition associated with a microbial infection, the method comprising administering into the middle ear of a pediatric patient in need thereof an aqueous thermoreversible gel composition comprising about 6.0% by weight of micronized ciprofloxacin and 15-17% by weight of poloxamer 407, wherein the composition is administered to the pediatric patient through a single, intratympanic injection to each infected ear, wherein the otic disease or condition is otitis media.