LATEX PARTICLES FOR AGGLUTINATION ASSAY

摘要

A latex particle for high-sensitive agglutination assay and a reagent for agglutination assay including the particle are provided. The latex particle barely initiates non-specific reactions and can readily prepare diagnostic agents. A latex particle for agglutination assay including a polymerizable monomer having a phenyl group, a polymerizable monomer having a phenyl group and a salt of sulfonic acid, and a polymerizable monomer represented by Formula (1):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒCH 2 =CR 1 -COO (CH 2 CH 2 O) n -R 2 €ƒ€ƒ€ƒ€ƒ€ƒ(1)
where R 1 represents a hydrogen atom or a methyl group; R 2 represents a hydrogen atom or a methyl group; and n is 1‰¤n<20, wherein the density of functional groups derived from the polymerizable monomer represented by Formula (1) on the surface of the particle is 0.05 to 0.5 µmol/m 2 .