发明名称 Process for preparing 2-chlorothiazole compounds
摘要 The invention relates to a process for preparing a compound of formula (I), in which X is CH or N, Y is NO2 or CN, Z is CHR3, O, NR3 or S, R1 and R2 are either each, independently of the other, hydrogen or unsubstituted or R4-substituted alkyl or together a two- or three-membered alkylene bridge or a two- or three-membered alkylene bridge in which one member is replaced by a hetero member selected from the group, consisting of NR5, O and S, R3 is H or unsubstituted or R4-substituted alkyl, R4 is an unsubstituted or substituted aryl or heteroaryl group, and R5 is H or alkyl, which comprises a) reacting a compound of formula (II) with a chlorinating agent or b1) initially reacting a compound of formula (IV) with a compound of formula (V) and b2) further reacting the compound of formula (II) obtainable thereby, with or without intermediate isolation, with a chlorinating agent, to intermediates used in this process, to the use of these intermediates and to a process for the preparation of these intermediates.
申请公布号 ZA9610046(B) 申请公布日期 1997.07.10
申请号 ZA19960010046 申请日期 1996.11.29
申请人 CIBA-GEIGY A.G. 发明人 HENRY SZCZEPANSKI;THOMAS GOBEL;OTTMAR FRANZ HUTER;ANTHONY CORNELIUS O'SULLIVAN;MARCEL SENN;THOMAS RAPOLD;PETER MAIENFISCH;THOMAS PITTERNA
分类号 C07D277/20;C07D;C07D277/32;C07D277/36;C07D417/06;C07D417/12;C07D417/14 主分类号 C07D277/20
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