发明名称 INHIBITOR OF ISCHEMIC DISORDERS
摘要 <p>It is intended to provide a drug which is efficacious in treating and preventing diseases wherein ischemia or an inflammatory substance associated with ischemia participates in the onset or worsening thereof. Because of containing as the active ingredient a substance selected from among farnesol, a farnesol derivative, a tocopherol derivative, a tocotrienol derivative, pharmacologically acceptable salts thereof and solvates thereof, the above-described inhibitor of ischemic disorders can exert therapeutic and preventive effects on diseases wherein ischemia or an inflammatory substance associated with ischemia participates in the onset or worsening thereof (for example, brain infarction, brain edema, cardiac infarction, etc.) not only by the administration in the acute ischemic stage but also by the therapeutic administration in the subacute and/or chronic stages after ischemic reperfusion. It is also intended to provide a farnesol carboxylic acid ester derivative and a method of producing the same.</p>
申请公布号 WO2009028707(A1) 申请公布日期 2009.03.05
申请号 WO2008JP65680 申请日期 2008.09.01
申请人 FUKUOKA UNIVERSITY;TAKATA, JIRO;MISHIMA, KENICHI;NAKASHIMA, MANABU;IWASAKI, KATSUNORI;MATSUNAGA, KAZUHISA;KARUBE, YOSHIHARU;FUJIWARA, MICHIHIRO 发明人 TAKATA, JIRO;MISHIMA, KENICHI;NAKASHIMA, MANABU;IWASAKI, KATSUNORI;MATSUNAGA, KAZUHISA;KARUBE, YOSHIHARU;FUJIWARA, MICHIHIRO
分类号 C07C229/08;A61K31/22;A61K31/223;A61K31/355;A61K31/665;A61P7/10;A61P9/10;C07C227/18;C07C229/12;C07C271/22;C07F9/655 主分类号 C07C229/08
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