Biosynthesis pathway for prenol in a recombinant microorganism

摘要

The present invention concerns a method for the biological preparation of prenol comprising culturing a microorganism genetically modified for the bioproduction of prenol, wherein the microorganism comprises a metabolic pathway for conversion of 3-methylcrotonyl-CoA into prenol by the action of an alcohol dehydrogenase enzyme and of an aldehyde dehydrogenase enzyme.

主权项

1. Method for fermentative production of prenol, comprising culturing a recombinant microorganism from Enterobacteriaceae family in a culture medium comprising a source of carbon, wherein in said microorganism, the prenol biosynthesis pathway comprises 3-methylcrotonyl-CoA as intermediate product, that is converted into prenol by action of an enzyme with alcohol dehydrogenase and aldehyde dehydrogenase activity.