| 发明名称 |
COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND/OR THERAPY OF DISORDERS THAT CORRELATE WITH DENND1A VARIANT 2 |
| 摘要 |
Pharmaceutical compositions and methods for the treatment of DENND1 A. V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1 A. V2 and methods for using the same are provided. |
| 申请公布号 |
US2016297873(A1) |
申请公布日期 |
2016.10.13 |
| 申请号 |
US201415036119 |
申请日期 |
2014.11.19 |
| 申请人 |
VIRGINIA COMMONWEALTH UNIVERSITY ;THE PENN STATE RESEARCH FOUNDATION |
发明人 |
MCALLISTER Janette M.;STRAUSS Jerome F.;CHRISTENSEN Neil D. |
| 分类号 |
C07K16/18;G01N33/68;C12N15/113 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising an antibody or an antigen binding fragment thereof, wherein said antibody or antigen binding fragment thereof specifically recognizes DENND1A.V2 protein and does not specifically recognize DENND1A.V1 protein. |
| 地址 |
Richmond VA US |
