发明名称 |
DNA strands useful for the synthesis of xanthophylls and the process for producing the xanthophylls |
摘要 |
Disclosed are the following DNA strands relating to the synthesis of keto group-containing xanthophylls such as astaxanthin and the like, and the techniques relating to the production of xanthophylls by genetic engineering: A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for converting a methylene group at the 4-position of a beta -ionone ring into a keto group. A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for converting a methylene group at the 4-position of a 3-hydroxy- beta -ionone ring into a keto group. A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for adding a hydroxyl group to the 3-carbon of a 4-keto- beta -ionone ring. It is possible to produce a variety of xanthophylls such as canthaxanthin, astaxanthin and the like by introducing the DNA strands into an appropriate microorganism such as Escherichia coli and the like.
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申请公布号 |
US6150130(A) |
申请公布日期 |
2000.11.21 |
申请号 |
US19990335919 |
申请日期 |
1999.06.18 |
申请人 |
KIRIN BEER KABUSHIKI KAISHA;MARINE BIOTECHNOLOGY INSTITUTE CO., LTD. |
发明人 |
MISAWA, NORIHIKO;KONDO, KEIJI;KAJIWARA, SUSUMU;YOKOYAMA, AKIHIRO |
分类号 |
C12N9/02;C12N15/53;C12P23/00;(IPC1-7):C12P23/00;C12P7/26 |
主分类号 |
C12N9/02 |
代理机构 |
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