发明名称 Drug complex
摘要 A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C1-4)alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.
申请公布号 US6838450(B2) 申请公布日期 2005.01.04
申请号 US20020155170 申请日期 2002.05.28
申请人 DAIICHI PHARMACEUTICAL CO., LTD;DRUG DELIVERY SYSTEM INSTITUTE, LTD. 发明人 INOUE KAZUHIRO;SUSAKI HIROSHI;IKEDA MASAHIRO;KUGA HIROSHI;KUMAZAWA EIJI;TOGO AKIKO
分类号 A61K47/48;(IPC1-7):A01N43/04;A61K31/715;A61K38/00 主分类号 A61K47/48
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