发明名称 |
Vectors For the Co-Expression of Membrane Domains of Viral Envelope Proteins and Uses Thereof |
摘要 |
The present invention discloses a vector for the coexpression of membrane domains of the envelope proteins of a virus, and also a method for producing homo- and/or hetero-oligomers of these domains. This vector comprises at least one region for replication and for maintenance of said vector in the host cell; a first region consisting successively, in said direction of translation of the vector, of a first promoter followed by a first sequence encoding a first chimeric protein comprising in particular a sequence encoding one of said at least two membrane domains; and a second region consisting successively, in said direction of translation of the vector, of a second promoter followed by a second sequence encoding a second chimeric protein comprising in particular a sequence encoding the other of said at least two membrane domains. The present invention is useful for the production of medicinal products for the treatment or prophylaxis of hepatitis C.
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申请公布号 |
US2008234184(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20040569882 |
申请日期 |
2004.08.19 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;COMMISSARIAT A L'ENERGIE ATOMIQUE |
发明人 |
FALSON PIERRE;MONTIGNY CEDRIC;PENIN FRANCOIS |
分类号 |
A61K38/00;A61P31/14;A61P43/00;C07K14/00;C07K14/18;C12N1/20;C12N1/21;C12N15/00;C12N15/51;C12P21/02;C12P21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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