发明名称 |
Anti-p53 Antibodies |
摘要 |
The present invention relates to nucleotide sequences which encode polypeptides of antibodies against the p53 protein in vertebrates, and to die polypeptides and antibodies (or fragments thereof) encoded by those nucleotide sequences. The invention also relates to nucleotide sequences and polypeptide sequences for use in the development of diagnostic and therapeutic compositions, and to methods of using those diagnostic and therapeutic compositions in the diagnosis and treatment of cancer, rheumatoid arthritis and other disease states which exhibit abnormalities of p53.
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申请公布号 |
US2008233120(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20070941588 |
申请日期 |
2007.11.16 |
申请人 |
ST. VINCENT'S HOSPITAL (SYDNEY) LIMITED |
发明人 |
WARD ROBYN LYNNE;COOMBER DAVID WILLIAM JOHN |
分类号 |
A61K39/395;G01N33/53;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61K49/00;A61K51/00;A61P9/00;A61P19/02;A61P35/00;A61P37/02;A61P43/00;C07H21/00;C07K16/18;C07K16/42;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12N15/02;C12P21/08;C12Q1/68;C12R1/19;C12R1/91;G01N33/574;G01N33/577 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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