ORALLY ADMINISTERED PREPARATION CONTAINING AT LEAT ONE PHARMACEUTICALLY ACTIVE SUBSTANCE IN A MATRIX CAPABLE TO SWELL IN AQUEOUS ENVIRONMENT

摘要

A tablet composed of co-adhesive layers comprises: (a) at least one matrix layer which (i) is swellable in an aqueous medium; (ii) contains at least one drug released in a retarded manner during the swelling, (iii) does not decompose during the swelling and (iv) contains crosslinked amylose; and (b) at least one adjuvant and/or substrate layer.