| 摘要 |
A system is provided for contamination free delivery and control of a flowab le medium contained in an enclosed flow path or a container. The device enables a flowable material to be formulated without anti-oxidants, preservatives or anti microbial agents. This provides the advantage of an enhanced therapeuti c effect for many medications, especially those which are considered labile. T he system provides a seat (100) and reversibly deformable seal (110) disposed i n the flow path; wherein the seal and seat are moveable between a closed and open state upon the deformation of the seal. In the closed state, the sealin g surface (114) between the seal and seat entraps one or more layers of the flowable material which forms a bonding action between the seal and seat to prevent entry of external matter into the flow path while at the same time forming a barrier against the back flow migration of contaminating matter.</ SDOAB>
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