| 摘要 |
<p>Disclosed is a method for preparing a compound of Formula 1 by contacting compound of Formula 2 with R1-NH<sub>2</sub> in the presence of a carboxylic acid and a method for preparing a compound of Formula 2 by contacting a compound of Formula 4 with phosphorus tribromide. ( 1, 2, 4 ) wherein R1 is H, C<sub>1</sub>_C<sub>4</sub> alkyl, cyclopropyl, cyclopropylmethyl or methylcyclopropyl; R2 is CH<sub>3</sub> or C1; R3 is C<sub>1</sub>_C<sub>6</sub>alkyl or C<sub>3</sub>_ C<sub>6</sub> alkenyl, each optionally substituted with up to 3 halogen and up to 1 phenyl; and X is C1 or Br. Also disclosed is a method for preparing a compound of Formula 5, wherein R4, R5, R6 and Z are as defined in the disclosure, using a compound of Formula 1 that is characterized by preparing the compound of Formula 1 by the method above.</p> |
