发明名称 |
FORMULATION COMPRISING A GEMCITABINE-PRODRUG |
摘要 |
This invention relates to pharmaceutical formulations of gemcitabine-[phenyl-benzoxy-L- alaninyl)]-phosphate, a monophosphate derivative of the well-known oncology drug gemcitabine. In particular, the invention relates to formulations which comprise a polar aprotic solvent, preferably dimethyl acetamide (DMA). Formulations comprising these solvent provide therapeutically effective treatments of gemcitabine-[phenyl-benzoxy-L- alaninyl)]-phosphate. The invention also relates to methods of using said formulations and kits comprising said formulations. |
申请公布号 |
SG11201608809R(A) |
申请公布日期 |
2016.11.29 |
申请号 |
SG11201608809R |
申请日期 |
2015.06.25 |
申请人 |
NUCANA BIOMED LIMITED |
发明人 |
GRIFFITH, HUGH;KENNOVIN, GORDON |
分类号 |
C07H19/10;A61K9/00;A61K9/08;A61K31/7068;A61K47/16;A61K47/20;A61K47/22;A61P35/00 |
主分类号 |
C07H19/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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