发明名称 |
TRICYCLIC COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS |
摘要 |
The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents A, R1, R2, R3a, R3b, R4a, R4b and n are as defined herein. The inventions also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds and methods of preparing the compounds. |
申请公布号 |
WO2016203347(A1) |
申请公布日期 |
2016.12.22 |
申请号 |
WO2016IB53398 |
申请日期 |
2016.06.09 |
申请人 |
PFIZER INC. |
发明人 |
CHAPPIE, Thomas Allen;CHANDRASEKARAN, Ramalakshmi Yegna;HELAL, Christopher John;LACHAPELLE, Erik Alphie;PATEL, Nandini Chaturbhai;SCIABOLA, Simone;VERHOEST, Patrick Robert;WAGER, Travis T. |
分类号 |
C07D487/14;A61K31/4985;A61K31/506;A61P25/28;C07D471/14;C07D471/22;C07D487/04;C07D491/147;C07D498/22;C07D513/14 |
主分类号 |
C07D487/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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