PROCEDIMIENTO PARA LA ELIMINACION DE VIRUS EN SOLUCIONES DE FIBRINOGENO DE APLICACION TERAPEUTICA.

摘要

The process starts with an adjusted purified fibrinogen solution, the adjusted purified solution is frozen and then thawed at a temperature between 5 and 20oC, the undissolved materials associated with the fibrinogen are subsequently separated, the temperature is adjusted and the resultant solution is finally subjected to nanofiltration using filters to a pore size smaller than 35 nm.