发明名称 COMPOSICION FARMACEUTICA QUE COMPRENDE: i) UNA BASE LIQUIDA CON 50-300mg/100ml DE SUCRALOSA PARA DISIMULAR SABOR AMARGO DE UN ACTIVO Y II) AL MENOS UN ACTIVO SELECCIONADO ENTRE ANTIHISTAMINAS, DESCONGESTIONANTES, ANTITUSIVOS, EXPECTORANTES, ANTIBIOTI
摘要 The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH from about 2 to about 5. The invention is further directed to medicinal compositions comprising such a liquid excipient base and unpleasant tasting medicines. Still further, the invention is directed to a method for taste masking unpleasant tasting medicines through their incorporation into the claimed liquid excipient bases.
申请公布号 CL2004000208(A1) 申请公布日期 2005.03.18
申请号 CL20040000208 申请日期 2004.02.06
申请人 WYETH 发明人 JAEGER DAVID;DICKERSON JAY;MOGAVERO ANABELLE
分类号 A61K47/36;A61K9/00;A61K31/715;A61K45/00;A61K47/26;(IPC1-7):A61K31/715 主分类号 A61K47/36
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