| 发明名称 |
4-(HETERO)ARYL SUBSTITUTED INDOLINONES |
| 摘要 |
The present invention relates to 4-arylindolinones of formula (I), as well a s pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention relates to methods for treating protein kinase related disorders. Formula (I) wherein: R1 is an optionally substituted aryl or heteroaryl substituent, R2-R5 are as in claim 1.
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| 申请公布号 |
CA2432114(A1) |
申请公布日期 |
2002.07.18 |
| 申请号 |
CA20012432114 |
申请日期 |
2001.12.20 |
| 申请人 |
SUGEN, INC. |
发明人 |
CHU, JI YU;ZHANG, FANG-JIE;KOENIG, MARCEL;WEI, CHUNG CHEN;LI, XIAOYUAN;ZHANG, RUOFEI;CUI, JINGRONG;TANG, PENG CHO;DO, STEVEN HUY;SHEN, HONG |
| 分类号 |
A61K31/136;A61K31/337;A61K31/404;A61K31/416;A61K31/4192;A61K31/4439;A61K31/454;A61K31/496;A61K31/513;A61K31/5377;A61K31/541;A61K31/55;A61K45/00;A61P3/10;A61P9/00;A61P9/10;A61P11/16;A61P13/08;A61P13/12;A61P17/06;A61P19/02;A61P29/00;A61P31/10;A61P35/00;A61P37/02;A61P43/00;C07D209/34;C07D209/42;C07D401/14;C07D403/06;C07D403/14;C07D413/14;C07D417/14;C07D487/04;(IPC1-7):C07D403/06 |
主分类号 |
A61K31/136 |
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