发明名称 |
Use of 4-[(4-thiazolyl)phenoxl] alkoxy-benzamidine derivatives for treatment of osteoporosis. |
摘要 |
This invention relates to a pharmaceutical composition containing 4-[(4-thiazolyl)phenoxyl]alkoxy-benzamidine derivatives expressed by the following formula 1 for the prevention and treatment of osteoporosis and more particularly, to the use of 4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxyl]pentoxy}-benzamidine or N-hydroxy-4-{5-[4-(5-iso-propyl-2-methyl-1,3-thiazol-4-yl)phenoxyl]pentoxy}-benzamidine expressed by the following formula 1, which is known as an antagonist of leukotriene-B4 receptor, as a pharmaceutical composition for the prevention and treatment of osteoporosis. [Formula 1], wherein, R is a hydrogen atom or a hydroxy group. |
申请公布号 |
ZA200400331(B) |
申请公布日期 |
2005.04.15 |
申请号 |
ZA20040000331 |
申请日期 |
2004.01.15 |
申请人 |
DONG WHA PHARM. IND. CO., LTD;SUH, HONG-SUK |
发明人 |
HONG-SUK SUH;PAN-SOO KIM;JEI-MAN RYU;EUN-JOO KIM;YONG-YOUP PARK;JIN-SOO LEE;YUN-HA HWANG;YONG-HO CHUNG;DO-HUI KIM |
分类号 |
C07D277/24;A61K31/095;A61K31/426;A61P9/10;A61P19/10;A61P43/00 |
主分类号 |
C07D277/24 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|