Bifidobacterium bifidum strains for application in gastrointestinal diseases

摘要

The present invention provides a strain of Bifidobacterium bifidum or mutant or variant thereof showing at least an adhesion of about 10 bacterial cells per mm2 of epithelial cell monolayer or having at least an adhesion index of 1.5 and a strain of Bifidobacterium bifidum or mutant or variant thereof being Bifidobacterium bifidum MIMBb75, deposited under deposit No. DSM 24514, or a mutant or variant thereof for use as probiotic, in foodstuff and/or as a medicament. Further provided is a probiotic for mulation, comprising any of the strains, mutants or variants mentioned above, uses of said probiotic formulation, strains, mutants and variants thereof and a method for producing said probiotic formulation.

主权项

1. A method of treatment, comprising administering to a subject in need thereof an effective amount of a probiotic formulation comprising a strain of Bifidobacterium bifidum MIMBb75, deposited under deposit No. DSM 24514, wherein the subject is in need of treatment of irritable bowel syndrome.