发明名称 |
Allergen dosage form |
摘要 |
The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided. |
申请公布号 |
US9408805(B2) |
申请公布日期 |
2016.08.09 |
申请号 |
US201414287920 |
申请日期 |
2014.05.27 |
申请人 |
ALK-Abello A/S;R.P. Scherer Technologies, LLC |
发明人 |
Jacobi Henrik Hugo;Lundegaard Annette Roemmelmayer;Houghton Christian Gauguin;Aasmul-Olsen Stig;Maerkedahl Lise Lund;Andersen Jan Sondergaard;Mallindine Kerry;Murray Owen James;Banbury Susan Gerrard;Wong Desmond Yik Teng;Garrett Lisa Marie;Hall Michael |
分类号 |
A61K39/36;A61P37/08;A61K9/00;A61K9/20;A61K39/35;A61K45/06;A61K39/00 |
主分类号 |
A61K39/36 |
代理机构 |
Womble Carlyle Sandridge & Rice LLP |
代理人 |
Womble Carlyle Sandridge & Rice LLP |
主权项 |
1. A method for administering an allergen to a mammal which comprises:
oromucosally administering to a mammal having at least one clinical allergy symptom an oromucosal dosage form comprising an effective dose of a major grass pollen allergen, and repeating the administration of an oromucosal dosage form comprising an effective dose of the major grass pollen allergen at least once daily, wherein the repeat administration does not comprise an up-dosing phase, and wherein the repeated administration of said major grass pollen allergen reduces the at least one clinical allergy symptom. |
地址 |
Horsholm DK |