| 摘要 |
PROBLEM TO BE SOLVED: To provide an antibody-drug conjugate useful as an antitumor drug which is excellent in terms of antitumor effect and safety of topoisomerase I inhibitor.SOLUTION: The present invention provides a following compound that is a water-soluble camptothecin derivative. HO-CH2-C(=O)-(NH-DX), where -(NH-DX) is a group, shown by a following formula, with the nitrogen atom of the amino group at position 1 as a connecting position.SELECTED DRAWING: None |
