| 摘要 |
<p>A method and apparatus for optically monitoring the concentration of singlet oxygen produced during photoradiation. A composite optical emission in the 1.27 micron frequency band is detected and electrically processed to separate a first component due to the decay of single oxygen from second unwanted component due to the fluorescence of the photosensitizing dye. A pulse excitation source (16) is used to excite the photosensitizing dye and a time domain signal processor (40), such as a box-car integrator (28), is used to separate and process the singlet oxygen emission component in the time domain. The magnitude and/or other characteristics of the singlet oxygen emission component can be used to determine properties of complex biological or other media. In a therapeutic environment the magnitude and/or characteristics of the singlet oxygen emission can be used by the treating physician to set a therapeutic light dosimetry.</p> |
