发明名称 |
Tetrahydrobenzothiazole analogues as neuroprotective agents |
摘要 |
This invention relates generally to tetrahydrobenzothiazole analogues and tetrahydrobenzooxyzole analogues, to pharmaceutical compositions which include these compounds and a pharmaceutically acceptable carrier, and to methods of treatment using these compounds. The invention also encompasses pharmaceutically acceptable esters, amides, and salts of such compounds. The invention further provides a method of reducing or delaying apoptosis in a population of cells, comprising contacting the population of cells with a tetrahydrobenzothiazole analogue or a tetrahydrobenzooxyzole analogue, thereby reducing or delaying apoptosis in the population of cells. |
申请公布号 |
AU7887501(A) |
申请公布日期 |
2002.01.21 |
申请号 |
AU20010078875 |
申请日期 |
2001.07.06 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED |
发明人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED;BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;NIGEL H GREIG;MARK MATTSON;XIAO-XIANG ZHU;QIAN-SHENG YU;HAROLD WAYNE HOLLOWAY |
分类号 |
A61P25/00;A61P25/16;A61P25/28;C07D263/58;C07D277/68;C07D277/82;C07D498/04;C07D513/04 |
主分类号 |
A61P25/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|