发明名称 |
NICOTINAMIDE BENZOFUSED-HETEROCYCLYL DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE4 ISOZYMES |
摘要 |
Compounds useful as inhibitors of PDE4 in the treatment of diseas s regulate d by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of Formula (1.0.0.). In said formula R5 and R6 are taken together to form a moiety of partial Formulas (1.1.1) through (1.1.5) or a pharmaceutically acceptable salt thereof.
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申请公布号 |
CA2398182(C) |
申请公布日期 |
2007.03.13 |
申请号 |
CA20012398182 |
申请日期 |
2001.01.30 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
CHAMBER, ROBERT JAMES;MARFAT, ANTHONY |
分类号 |
C07D413/12;A61K31/4439;A61K31/665;A61K31/67;A61K45/00;A61K45/06;A61P1/04;A61P1/16;A61P3/10;A61P7/00;A61P7/06;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P13/00;A61P13/02;A61P13/08;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P17/14;A61P19/02;A61P19/08;A61P19/10;A61P21/00;A61P21/04;A61P25/00;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P27/02;A61P29/00;A61P31/10;A61P31/12;A61P31/18;A61P35/00;A61P37/04;A61P37/06;A61P43/00;C07D213/00;C07D271/00;C07D285/00;C07D401/12;C07D401/14;C07D413/14;C07D417/12;C07D417/14 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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