发明名称 |
RECOMBINANT PARTICLE BASED VACCINES AGAINST HUMAN CYTOMEGALOVIRUS INFECTION |
摘要 |
The invention relates to gene and protein assemblies in the form of virus-like particles and protein complexes for use as prophylactic or therapeutic vaccines, and diagnostic and R&D tools for human cytomegalovirus (HCMV) and other herpes viruses. The virus-like particles comprise one or more capsid proteins from a herpes virus or a retrovirus, three or more CMV surface proteins and optionally tegument proteins. The assemblies are prepared using a technology combining recombinant DNA with disposable cell culture and purification techniques. |
申请公布号 |
EP2914284(B1) |
申请公布日期 |
2016.09.21 |
申请号 |
EP20130789738 |
申请日期 |
2013.10.30 |
申请人 |
PFIZER INC. |
发明人 |
WELLNITZ, SABINE;JOHN, CORINNE;SCHAUB, CHRISTIAN |
分类号 |
A61K39/245 |
主分类号 |
A61K39/245 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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