发明名称 PIPERAZINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF ASTHMA
摘要 The invention provides compounds of Formula (I): wherein: R<SUP>1</SUP>-R<SUP>4</SUP>, A, L, and X have any of the values defined in the specification that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use, and methods and intermediates useful for preparing them.
申请公布号 PL370746(A1) 申请公布日期 2005.05.30
申请号 PL20020370746 申请日期 2002.11.25
申请人 F.HOFFMANN-LA ROCHE AG 发明人 DU BOIS DAISY JOE;KERTESZ DENIS JOHN;SJOGREN ERICK BRIAN;SMITH DAVID BERNARD;WANG BEIHAN
分类号 C07D295/12;A61K31/495;A61K31/496;A61P1/04;A61P11/06;A61P27/16;A61P37/08;A61P43/00;C07D241/04;C07D295/084;C07D295/135;C07D307/22;C07D333/24 主分类号 C07D295/12
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