CROSS-REACTIVE ANTI-PAD ANTIBODIES

摘要

Disclosed herein are cross-reactive anti-peptidylarginine deiminase (PAD) antibodies and fragments and variants thereof capable of binding to at least PAD2 and PAD4 and use of such anti-PAD antibodies or fragment or variants thereof in the treatment of autoimmune diseases characterized by extracellular citrullination, in particular rheumatoid arthritis (RA).