发明名称 |
Remedium for overaktiv blaere, omfattende eddiksyreanilidderivat som aktiv ingrediens. |
摘要 |
(R)-2-(2-aminothiazol-4-yl)-4'-Ä2-Ä(2-hydroxy-2-phenylethyl)aminoÜethylÜacetic acid anilide or its salt shows a potent bladder relaxation effect in "isolated rat bladder smooth muscle relaxation test", dose-dependently lowers the contraction frequency of rhythmic bladder contractions in "rat rhythmic bladder contraction measurement test" and, moreover, prolongs the urination intervals in "urination functions measurement test on cyclophosphamide-induced overactive bladder model rat". Owing to these effects, the above compound is useful as a remedy for ovaractive bladder. |
申请公布号 |
NO20052691(D0) |
申请公布日期 |
2005.06.06 |
申请号 |
NO20050002691 |
申请日期 |
2005.06.06 |
申请人 |
YAMANOUCHI PHARMACEUTICAL CO LTD |
发明人 |
MARUYAMA TATSUYA;TAKASU TOSHIYUKI;SATO SHUICHI;UKAI MASASHI |
分类号 |
A61K31/426;A61P13/00;A61P13/10;C07D277/40;(IPC1-7):A61K |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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