| 发明名称 |
PROCESS FOR THE PREPARATION OF AN OPTICALLY ACTIVE LACTONE, AND STARTING PRODUCTS FOR THE PROCESS |
| 摘要 |
A process for the manufacture of the optically active lactone of the formula <IMAGE> I wherein R represents the benzyl group, is described. In this process an optically active compound of the formula <IMAGE> II wherein R has the above significance and R1 signifies the cholesteryl or the cyclohexyl group, is reduced with a dialkylaluminium hydride or a complex borohydride. The compound of formula I is a known, valuable intermediate for, inter alia, (+)-biotin. |
| 申请公布号 |
DE3268046(D1) |
申请公布日期 |
1986.01.30 |
| 申请号 |
DE19823268046 |
申请日期 |
1982.09.25 |
| 申请人 |
F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT |
发明人 |
PAULING, HORST, DR.;WEHRLI, CHRISTOF;VORSANGER, JEAN-JACQUES, DR. |
| 分类号 |
C07D233/32;C07D491/04;C07D491/048;C07J43/00;(IPC1-7):C07D491/048;C07D233/22 |
主分类号 |
C07D233/32 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
