| 摘要 |
<p>An economically advantageous and industrially appropriate process for producing 3-amino-2-hydroxypropionic acid derivatives (1) without resort to any dangerous reagents characterized by comprising treating an N-protected-3-amino-2-hdyroxypropionic acid derivative (2) having a contrary configuration at the carbon atom at the 2-position to a compound (1) with an agent for introducing a leaving group to thereby convert the compound (2) into an N-protected-3-amino-propionic acid derivative (3), then treating the compound (3) with a basic substance to give a substituted 3-amino-2-hydroxypropionic acid derivative (4) having an inversed configuration at the carbon atom at the 2-psoition, and then converting the compound (4) into the 3-amino-2-hydroxypropionic acid derivative (1).</p> |
