| 主权项 |
1. A test element configured for determining an analyte, comprising:
(i) a coenzyme-dependent dehydrogenase or a substrate for such an enzyme, the dehydrogenase being selected from the group consisting of lactate dehydrogenase (E.C.1.1.1.27, 1.1.1.28), malate dehydrogenase (E.C.1.1.1.37), glycerol dehydrogenase (E.C.1.1.1.6), alpha-hydroxybutyrate dehydrogenase, sorbitol dehydrogenase, and amino acid dehydrogenase and (ii) a compound of the following general formula (I) as the coenzyme: in which A=adenine or an analogue thereof, T=in each case independently denotes O, S, U=in each case independently denotes OH, SH, BH3−, BCNH2−, V=in each case independently denotes OH or a phosphate group, W=COOR, CON(R)2, COR, CSN(R)2 in which R in each case independently denotes H or C1-C2-alkyl, X1, X2=in each case independently denote O, CH2, CHCH3, C(CH3)2, NH, NCH3, Y=NH, S, O, CH2, Z=a residue comprising a cyclic group with 5 C atoms which optionally contains a heteroatom selected from O, S and N
and optionally one or more substituents, and a residue CR42 wherein CR42 is bound to the cyclic group and to X2,where R4=in each case independently denotes H, F, Cl, CH3,provided that Z and the pyridine residue are not linked by a glycosidic bond, or a salt or optionally a reduced form thereof. |
