发明名称 未分化細胞除去方法
摘要 An object of the present invention is to provide a method for introducing a target substance into undifferentiated cells, and a carrier therefor, whereby the target substance can be specifically introduced into the undifferentiated cells by contacting the undifferentiated cells with an rBC2LCN-target substance fusion product in which rBC2LCN lectin is fused to the target substance. Particularly, an rBC2LCN-toxin fusion product in which rBC2LCN lectin is fused to a toxin functioning in cells or its domain having the ability to kill cells functions as an agent for eliminating undifferentiated stem cells and can be administered into a medium after inducing the differentiation of the stem cells to reliably kill only the stem cells in an undifferentiated state.
申请公布号 JP5985735(B2) 申请公布日期 2016.09.06
申请号 JP20150500284 申请日期 2014.02.13
申请人 国立研究開発法人産業技術総合研究所 发明人 舘野 浩章;伊藤 弓弦;小沼 泰子;平林 淳;浅島 誠
分类号 C12N15/09;C07K14/42;C07K19/00;C12N5/10;G01N21/76 主分类号 C12N15/09
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