发明名称 |
Method of administering hyaluronan formulation for preventing and ameliorating osteoarthritis |
摘要 |
Disclosed is a method for mitigating or ameliorating osteoarthritis in vertebrate subjects including administering to a subject a therapeutically effective amount of an exogenous hyaluronan formulation. Also disclosed is an oral or parenteral hyaluronan composition comprising a polydisperse hyaluronan and a pharmaceutically acceptable carrier, and a method of manufacturing the composition. |
申请公布号 |
US9492381(B1) |
申请公布日期 |
2016.11.15 |
申请号 |
US201314054928 |
申请日期 |
2013.10.16 |
申请人 |
Reyn Pharma, LLC |
发明人 |
Smith James D. |
分类号 |
A61K31/728;A61K9/00 |
主分类号 |
A61K31/728 |
代理机构 |
Curatolo Sidoti Co., LPA |
代理人 |
Curatolo Sidoti Co., LPA ;Sidoti Salvatore A.;Curatolo Joseph G. |
主权项 |
1. A method for slowing, attenuating, mitigating, and/or ameliorating the loss of articular cartilage in a vertebrate subject, the method comprising orally administering a liquid composition comprising a therapeutically effective amount of exogenous hyaluronan composition comprising hyaluronan polymer and a pharmaceutically acceptable carrier to the subject, wherein the pH of the composition is about 2.5 to about 4.5. |
地址 |
Lexington KY US |