| 摘要 |
PURPOSE:To obtain an excellent potency over a long period of time by covalent bonding protein or peptide having cell adhering and growing effects via a hydroxyl group, carboxyl group, etc., on the surface of a tube consisting of a porous synthetic high polymer. CONSTITUTION:This artificial blood vessel is so formed that the vessel forms an inside membrane rapidly after transplantation and that the formed inside membrane exists stably over a long period of time and can impart the good potency. The tube is formed by covalent bonding the protein or peptide having the cell adhering and growing effects via the hydroxyl group, carboxyl group, epoxy group or amino group on the surface of the tube consisting of the porous synthetic high polymer. The ratio of the area of the synthetic high polymer occupying the inside cavity area of the tube consistin9 of the Porous synthetic high polymer is set at 15 to 80%. Stretched polytetrafluoroethylene is used as this porous synthetic high polymer. At least one kind selected from collagen, gelatin, laminine, etc., is used for the protein. |
