发明名称 |
NUCLEIC ACID TRANSPORTERS AND MEDICINAL COMPOSITIONS FOR GENE THERAPY |
摘要 |
<p>A novel nucleic acid carrier and a pharmaceutical composition for gene therapy are disclosed. The nucleic acid carrier of this invention is characterized by containing a polypeptide comprising diaminobutyric acid with a suitable number of residues and/or a pharmaceutically acceptable salt thereof. The nucleic acid carrier of this invention can form a complex with a variety of therapeutic genes that is safe and has extremely low immunogenicity (the pharmaceutical composition of this invention); and it can allow the therapeutic gene to be introduced into cells efficiently and safely whereby high expression of the gene in the cells can be realized. <IMAGE></p> |
申请公布号 |
EP1132099(A1) |
申请公布日期 |
2001.09.12 |
申请号 |
EP19990972111 |
申请日期 |
1999.11.17 |
申请人 |
HISAMITSU PHARMACEUTICAL CO. INC. |
发明人 |
GOTO, TAKESHI;YONEMURA, K.;KUWAHARA, T.;OYA, M.;AKIYAMA, K. |
分类号 |
A61K48/00;C12N15/87;(IPC1-7):A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|