发明名称 ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
摘要 Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
申请公布号 PH12013502285(A1) 申请公布日期 2016.08.08
申请号 PH12013502285 申请日期 2013.11.11
申请人 AMGEN INC. 发明人 JACKSON, SIMON, MARK;WALKER, NIGEL PELHAM, CLINTON;PIPER, DEREK, EVAN;SHAN, BEI;SHEN, WENYAN;CHAN, JOYCE CHI, YEE;KING, CHADWICK, TERENCE;KETCHEM, RANDAL, ROBERT;MEHLIN, CHRISTOPHER;CARABEO, TERESA, ARAZAS;CAO, QIONG
分类号 A61K39/395;A61P3/06;C07K16/40 主分类号 A61K39/395
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