发明名称 |
XANTHINE DERIVATIVES, THEIR USE AS A MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THE SAME |
摘要 |
The invention relates to a xanthine derivative defined by chemical formula I or a salt thereof, its use as a medicament, especially for use in the treatment of serotonin-related diseases or disorders, and a pharmaceutical preparation comprising the xanthine derivative. The novel xanthine compounds are capable of inhibiting tryptophan hydroxylases (TPH) involved in the biosynthesis of serotonin and are effective in influencing the serotonin level in the body. |
申请公布号 |
WO2016135199(A1) |
申请公布日期 |
2016.09.01 |
申请号 |
WO2016EP53872 |
申请日期 |
2016.02.24 |
申请人 |
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN;FORSCHUNGSVERBUND BERLIN E.V. |
发明人 |
BADER, Michael;SPECKER, Edgar;MATTHES, Susann;SCHÜTZ, Anja;MALLOW, Keven;GROHMANN, Maik;NAZARÉ, Marc |
分类号 |
C07D487/04;A61K31/522;A61P3/04;A61P11/06;A61P19/10;A61P25/18;A61P25/24;A61P29/00;A61P35/00;C07D519/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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